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The skin is the second largest organ in the body after the skeleton and of primary importance, integral to the survival of mammalian life, but often overlooked when examining the health and welfare of an individual. The heterogeneous skin structure is derived from the ectoderm and mesoderm of an embryo giving rise to the epidermis and dermis respectively. Within these generalized layers are specialized appendages also derived from the ectoderm and/or mesoderm including sensory nerves, sweat glands and hair follicles. The skin as a whole rests on subcutaneous tissue largely composed of a loose mesh of collagen fiber, fat cells and muscle tissue.
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